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This article suggests a framework for intention to treat

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pandora rings Loss to follow up is often hard to avoid in randomised trials. This article suggests a framework for intention to treat analysis that depends on making plausible assumptions about the missing data and including all participants in sensitivity analysesThe intention to treat principle requires all participants in a clinical trial to be included in the analysis in the groups to which they were randomised pandora earrings, regardless of any departures from randomised treatment.1 This principle is a key defence against bias, since participants who depart from randomised treatment are usually a non random subset whose exclusion can lead to serious selection bias.2However, it is unclear how to apply the intention to treat principle when investigators are unable to follow up all randomised participants. Our aim is not to describe specific methods for analysing missing data, since these are described elsewhere,9 10 but to provide the framework within which methods can be chosen and implemented. pandora rings

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pandora jewellery Among population samples, 11 studies provided data with lifetime abstainers as the reference group and 14 with current abstainers. The pooled risk for IHD incidence among chronic heavy drinkers in comparison to lifetime abstainers was RR=1.04, 95% CI 0.83 to 1.31, n=11 studies, figure 1), IHD mortality risk was similar (RR=1.00, 95% CI 0.74 to 1.36). Heterogeneity was moderate (for IHD incidence I2=54%) pandora jewellery.

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